CTE Task: Blood Types and Blood Transfusions​​

Click here to download the teacher resource for this lesson.


Anatomy & Physiology


One hour


Task Description


Students will watch a blood type video (10:45) and fill out the video guide then create a paper slide video to explain the concepts of blood typing and transfusions including information on the universal donor and the universal recipient.

18) Breakdown the roles of antigens and antibodies in the blood while explaining the ABO system and Rh classification system. In a lab setting with simulated blood, determine the ABO and Rh of samples with an explanation of results including a description of cross-matching and the causes and possible outcomes of a transfusion reaction.

 Content Understandings

Extending Understandings

Upon successful completion of these tasks students will demonstrate the ability to:

  1. Explain the functions of antigens and antibodies in the blood.
  2. Link the antigen/antibody information to blood types.
  3. Describe blood typing
  4. Explain blood transfusions and transfusion reactions.


To move students towards deeper understanding, they should be given opportunities to:

  1. Volunteer to help organize a blood drive.
  2. Practice a simulated blood typing activity

Support Strategies

If students are struggling to access this task, additional supports and strategies could be employed as students are engaging with the task.

Key Terms

Sentence Frames

Scaffolded Questions










  1. The _________ carries oxygen in the blood.
  2. The _______ on the erythrocyte is what indicates the blood type.
  3. _________ recognize foreign bodies and attach to them so they cannot cause problems.
  4. During a blood typing test, ____________, or clumping, is what the lab tech looks for to determine blood type.
  1. What is the function of plasma?
  2. What is the function of the red cell?
  3. Why does blood have to be compatible for a transfusion?
  4. What happens in a transfusion reaction?

Additional Resources

American Red Cross. (n.d.). Facts about Blood and Blood Types. Click here for link

Bozeman Science. (2012). Blood Types. [Video]. YouTube. Click here for link


Student Resources

Click here to download the student resource for this lesson. 

Blood Types Student Materials

  1. Watch the Bozeman Science Blood Types video here and fill in this guided reading sheet.
  2. The two main categories of blood typing covered in this video are _________ typing and Rh factor typing.
  3. When we talk about blood types we are talking about _________ that are found on the surface of the erythrocyte.
  4. ______ on the surface of the blood act as antigens.
  5. A blood has ___antigens and ___ antibodies
  6. B blood has __ antigens and ___ antibodies.
  7. AB blood has ___antigens and ___ antibodies.
  8. O blood has __ antigens ___antibodies.
  9. If a person with type A blood (remember it contains A antigens & B antibodies) is given a transfusion of O blood, what happens?
  10. If that same person gets a transfusion of B blood, what happens?
  11. Why is getting the wrong type of blood dangerous?
  12. If a person with AB blood (remember it contains both A antigens & B antigens but no antibodies) is given a transfusion of B blood, what happens?
  13. What is a universal recipient? What blood type is the universal recipient?
  14. Stop the video at 4:15


  1. Fill in the following chart and indicate the universal donor and universal recipient:

Blood Type



Can Give Blood (red cells) to:

Can Receive Blood (red cells) from:






















For more information, click here


  1. Create a Paper Slide Video about blood typing to share with your teacher and classmates. Your video must include the terms in the table below. For directions on how to create a paper slide video, click here



NOTE: do not upload your video. Wait for your teacher to give you directions for submitting your work.

Your paper slide video must include the following terms/concepts:


B Antigen




A Antibody

Universal Donor

Transfusion Reaction


B Antibody

Universal Recipient




ABO typing


A Antigen


Rh typing